Hormonal homeostasis in women of reproductive age with adenomyosis

The problem of adenomyosis is particularly relevant for patients reproductive age, as it accompanied by the significant disturbances menstrual and generative functions. article presents results studying condition hypothalamic-pituitary-ovarian system in women age with adenomyosis.The objective: to study state benign endometrial myometrial pathology.Materials methods. main group included 120 pathology (adenomyosis, hyperplasia combined pathology), control 40 healthy without gynecological pathology. functional was evaluated levels follicle-stimulating hormone (FSH), luteinizing (LH), prolactin (PRL), estradiol (E2) progesterone (P) blood serum different phases cycle.Results. In adenomyosis, pathology, there hyperproduction gonadotropic hormones an increase their secretion level compared a women: average concentration FSH, regardless phase cycle, increased 1.9 times (p<0.05), LH – 2.2 times, PRL 2 which indicates presence hyperprolactinemia. Both I II occurrence additional FSH peaks from basal determined group, reached ovulatory peak. hyperestrogenemia during entire cycle hypoprogesteronemia were detected. expression hormonal shifts depended on pathology) woman.Conclusions. indicators prolactin-stimulating activity pituitary gland uterine confirm participation complex processes regulation system.